Custom companion diagnostic

Custom companion diagnostic, a must in drug development

At the dawn of the precision medicine era, targeting the right subset of patients and predict who will or will not respond to the treatment is of utmost importance. In these cases, relevant tools that would detect a set of biomarkers which would determine if a certain patient can react to a specific treatment and then to follow the patient response to that treatment are needed. These are called companion diagnostic and ideally each treatment would come with its own companion diagnostic. One of the best known pairs of therapeutic and his companion diagnostic is the Herceptin(R) and HerceptestTM to evaluate HER2 overexpression and specifically treat those patients.

The different pathways of interest for a certain pathology are monitored during the development and selection of bioactive compounds. Sometimes available commercial antibodies targeting their effective pathways are not necessarily specific for relevant samples or may not work in your desired applications. In many cases, the targeted pathways are so innovative that no products are available commercially. Whether the goal is to determine the phosphorylation level of specific sites or the proportion of different isoforms of a protein in your samples, custom diagnostic companion development should be part of the drug development from the start.

At MédiMabs, we can help you with your projects and find a custom-tailored solution to your project using our expertise in antibody developmentcustom multiplexing tools and diagnostic kit validation.

Written by
MédiMabs’ Team
Change my preferences

We use cookies to facilitate your navigation and enable certain features. You can see detailed information about all cookies in each consent category below.

Functional cookies (Required)

These cookies are essential for the proper functioning of our website; that’s why you can’t delete them.

Statistical cookies

These cookies allow us to know the use made of our site and its performance, to establish usage statistics and to determine the volumes of attendance and use of the various elements.

Advertising cookies

These cookies are used to provide visitors with personalized advertisements based on previously visited pages and to analyze the effectiveness of the advertising campaign.

Confirm my selection

This site uses cookies, deposited by our website, in order to improve your browsing experience. For more information on the purposes and to customize your preferences by type of cookies used, please visit our privacy policy page.

Accept all
Manage my preferences