MédiMabs Clones
A blog about science
hnRNP A1: The nuclear DJ fine-tuning antiviral immunity
In the cell’s nuclear control room, RNA-binding proteins (RBPs) are the DJs of gene expression. In a new study, Deshaies et al. (1) explore two isoforms of hnRNP A1 (A1 and A1B members of the hnRNP family) involved in RNA splicing, transport, and metabolism. While both isoforms are structurally similar and co-expressed across tissues, they […]
Latest articles
Valentine’s day dimers
When one and one make two. Dimerization is an important process in biology and especially in signal transduction. Receptor tyrosine kinases...
MédiMabs’ Team • Feb 14 • 2 minutes read
Happy new year and MIMs meeting
Another great occasion to discuss about immunology in Montreal organized by the (Montreal Immunology Meeting) MIM committee. We hope to meet you...
MédiMabs’ Team • Jan 31 • 1 minutes read
Which FGFR isoform drives cancer?
The promise of FGFR inhibitors in the clinic, but which FGFR isoform drives cancer?Urothelial cancer (UC) is the fifth most...
MédiMabs’ Team • Jan 31 • 5 minutes read
Angiogenesis in cancer, role of Endoglin (CD105)
When tumor cells are too far from blood supply, the different signals associated with hypoxia will be emitted. This will...
MédiMabs’ Team • Dec 06 • 2 minutes read
Another great 5 à 7 of the Montreal Immunology Meetings yesterday.
Yesterday, the second 5 à 7 from the 2018-2019 season of the was held in downtown Montréal. Again it was a...
MédiMabs’ Team • Dec 06 • 1 minutes read
The budding yeast, a classic cell cycle regulation model
The budding yeast (Saccharomyces cerevisiae) model has shown to be a powerful tool to study eukaryotic cell cycle regulation. The...
MédiMabs’ Team • Nov 22 • 2 minutes read
New publication! MM-0015-P
The presence of extracellular amyloid-beta plaques and tau neurofibrillary tangles has been a key neuropathological signature of Alzheimer's disease (AD)...
MédiMabs’ Team • Nov 22 • 5 minutes read
Biotech-Connect show of the McGill Bellini Life Sciences Complex this Thursday November 8
Held at the Bellini building of the McGill Life Science Complex, this biotech-connect show is a good opportunity to ask...
MédiMabs’ Team • Nov 06 • 1 minutes read
TLR4, 20 years later
20 years ago, in 1998, two research groups, Bruce Beutler’s and Shizuo Akira’s, have identified TLR4 as the LPS (Lipopolysaccharide)...
MédiMabs’ Team • Oct 31 • 2 minutes read
Akt activation pathway
Akt is a subfamily of serine/threonine kinases (Protein Kinase B) that includes AKT1, AKT2, and AKT3. Akt resides in the...
MédiMabs’ Team • Oct 26 • 2 minutes read