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IntelliStem

INTELLiSTEM PARTNERS WITH MONTREAL-BASED MÉDIMABS TO CREATE A BIOTECH POWERHOUSE PLATFORM

Halloween - Abeta

The exhumation of a possible treatment against the “brain-eating” Alzheimer’s disease

RPTP and synaptogenesis

Receptor protein tyrosine phosphatases (RPTPs) are protein family with implications in neuron development and axonal growth.  RPTPs implications in synaptogenesis, through the formation of trans-synaptic adhesion complexes, have been studied over the past decades. (1) The ability to control this process would be a key element for the development of neuro-regenerative therapy.

E-cadherin

The epithelial cell phenotype is defined by a cell organization that are structured in a single layer also called cell sheet. Typical epithelial cells have basal and apical polarity. On the other hand, the mesenchymal phenotype is associated with motility and invasiveness. In a physiological context, these phenotypes are intrinsic of these cell functions, for example the intestinal mucosa and his cell wall that mediates the entrance of nutrients in the bloodstream or the immune cells that migrate to the foci of infection.

Multiplexed immunoassays

 

Individually united, the advantage of Parallex Bioassay multiple singleplexing solution.

Microbiota and cancer immunotherapy

Four years ago, two different research teams have highlighted the possibility that the composition of the gut microbiota could modulate the efficacy of the cancer immunotherapy based on immune checkpoint inhibitors PD-L1 (1) and CTLA-4 (2).

Our antibodies at work

 

Another publication using our MM-0289-APC 28B7 for p24 double staining detection of HIV+ cells.

PSMA as a theranostic target

 

 Prostate cancer is the 3rd lethal type of cancer in the United States. Its diagnostic and stage assessment is done by histological analysis of microbiopsy, imagery, and serum marker evaluation. (1)

A receptor for cellular infiltration

CD44 role in T cell extravasation to inflammation site and cancer metastatic potential.

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