The epithelial cell phenotype is defined by a cell organization that are structured in a single layer also called cell sheet. Typical epithelial cells have basal and apical polarity. On the other hand, the mesenchymal phenotype is associated with motility and invasiveness. In a physiological context, these phenotypes are intrinsic of these cell functions, for example the intestinal mucosa and his cell wall that mediates the entrance of nutrients in the bloodstream or the immune cells that migrate to the foci of infection.
