This receptor tyrosine kinase is involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to subfamily of receptor tyrosine kinases with homology to Dictostelium discoideum protein discoidin I in their extracellular domain and are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract and brain. In addition, it is significantly overexpressed in several human tumors. [Provided by RefSeq]
CAK, CD167, EDDR1, NEP, NTRK4, PTK3A, RTK6
ECD of recombinant DDR1, aa: Asp21-Thr416
CR - 005 (generated by CCAB)
hIgG1; also available as mIgG1, scIgG1, schmIgG2a
Lyophilized protein A purified in PBS pH7.4
Recommend starting dilution:
Reconstitute with deionized water. Optimal dilution has to be determined by the user.
Research Use Only; Manufactured by CCAB under a license using Life Technologies proprietary cell lines.
Lyophilized antibodies can be kept at 4ºC for up to 3 months and should be kept at -20ºC for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80ºC) or kept at 4ºC for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy.