MédiMabs Clones
A blog about science
When Brain Beavers Build Too Big: Breaking the Glycogen Dam in Tauopathy
In the complex landscape of neurodegenerative disorders like Alzheimer’s disease and frontotemporal lobar degeneration (FTLD), an interesting case of metabolic misbehavior has been identified by a research team at the Buck Institute of Research on Aging (1). Think of glycogen, the brain’s emergency energy reserve, as the building material. In affected neurons, the tau protein […]
hnRNP A1: The nuclear DJ fine-tuning antiviral immunity
In the cell’s nuclear control room, RNA-binding proteins (RBPs) are the DJs of gene expression. In a new study, Deshaies et al. (1) explore two isoforms of hnRNP A1 (A1 and A1B members of the hnRNP family) involved in RNA splicing, transport, and metabolism. While both isoforms are structurally similar and co-expressed across tissues, they […]
HIV’s Hidden Roots: Why Curing the Virus is Like Eradicating a Deeply Embedded Plant
Imagine the HIV reservoir in people on successful antiretroviral therapy (ART) not as a single, easily cornered fugitive, but as seeds from an incredibly stubborn weed, scattered throughout the complex garden of your body. A new research article from Belgium (1) reveals how these “seeds” have taken root in the fertile ground of the blood, […]
