Progressive deposition of insoluble aggregates of the 39 to 43 amino acid amyloid β (Aβ) peptide derived from the proteolytic cleavage of the amyloid β-protein precursor (AβPP), gives rise to one of the pathological hallmarks of Alzheimer’s disease (AD). The formation of Aβ fragments is a critical determinant in unleashing AD neuropathology.
Beta-amyloid, ABP, amyloid peptide
Lyophilized protein G purified in PBS pH7.4
Recommend starting dilution:
If reconstituted with deionized water in 100 µL: IHC / ICC 1:500. Optimal dilution has to be determined by the user.
Lyophilized antibodies can be kept at 4ºC for up to 3 months and should be kept at -20ºC for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80ºC) or kept at 4ºC for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy.