MM-0031
Huntingtin-Interacting Protein 1 (HIP1) Rabbit Polyclonal Antibody
Application :
IF, WBReactivity :
Human, RatHost :
RabbitClonality :
PolyclonalOverview
Target
Huntingtin-Interacting Protein 1 (HIP1)
Target background
Hungtinton’s disease (HD) is an inherited neurodegenerative disorder characterized by the expression of an expanded polyglutamine tract in the protein huntingtin. HIP1 (huntingtin interacting protein 1) binds to normal huntingtin but this interaction is lost in HD. HIP1 also binds to components of clathrin-coated pits and vesicles and is a marker of clathrin-coated membranes. HIP1 expression levels are altered in several types of cancer.
Target alias
HIP1
Immunogen
peptide in C term
Specificity
The antibody recognizes the C-terminal portion of HIP1
Clone ID
---
Preservative
None
Format
Immunogen affinity purified in glycerol/PBS pH7.4
Recommend starting dilution
If diluted with deionized water in 100 µL: WB 1:500-1:2500; IF 1:10-1:100. Optimal dilution has to be determined by the user.
Limitations
Research Use Only
Storage
Antibodies diluted in glycerol can be kept at 4ºC for up to 2 months and should be kept at -20ºC for long-term storage (1 year). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. After the maximum long-term storage period (1 year -20ºC or 2 months 4ºC) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy.
References
Product datasheet
Huntingtin-Interacting Protein 1 (HIP1) Rabbit Polyclonal Antibody
SKU: MM-0031
100 µL
Overview
Target
Huntingtin-Interacting Protein 1 (HIP1)
Target background
Hungtinton’s disease (HD) is an inherited neurodegenerative disorder characterized by the expression of an expanded polyglutamine tract in the protein huntingtin. HIP1 (huntingtin interacting protein 1) binds to normal huntingtin but this interaction is lost in HD. HIP1 also binds to components of clathrin-coated pits and vesicles and is a marker of clathrin-coated membranes. HIP1 expression levels are altered in several types of cancer.
Target alias
HIP1
Immunogen
peptide in C term
Specificity
The antibody recognizes the C-terminal portion of HIP1
Clone ID
---
Preservative
None
Format
Immunogen affinity purified in glycerol/PBS pH7.4
Recommend starting dilution
If diluted with deionized water in 100 µL: WB 1:500-1:2500; IF 1:10-1:100. Optimal dilution has to be determined by the user.
Limitations
Research Use Only
Storage
Antibodies diluted in glycerol can be kept at 4ºC for up to 2 months and should be kept at -20ºC for long-term storage (1 year). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. After the maximum long-term storage period (1 year -20ºC or 2 months 4ºC) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy.