MM-0031

Huntingtin-Interacting Protein 1 (HIP1) Rabbit Polyclonal Antibody

Application :

IF, WB

Reactivity :

Human, Rat

Host :

Rabbit

Clonality :

Polyclonal

USD $335.00

/ 100 µL

Overview

Target

Huntingtin-Interacting Protein 1 (HIP1)

Target background

Hungtinton’s disease (HD) is an inherited neurodegenerative disorder characterized by the expression of an expanded polyglutamine tract in the protein huntingtin. HIP1 (huntingtin interacting protein 1) binds to normal huntingtin but this interaction is lost in HD. HIP1 also binds to components of clathrin-coated pits and vesicles and is a marker of clathrin-coated membranes. HIP1 expression levels are altered in several types of cancer.

Target alias

HIP1

Immunogen

peptide in C term

Specificity

The antibody recognizes the C-terminal portion of HIP1

Clone ID

---

Preservative

None

Format

Immunogen affinity purified in glycerol/PBS pH7.4

Recommend starting dilution

If diluted with deionized water in 100 µL: WB 1:500-1:2500; IF 1:10-1:100. Optimal dilution has to be determined by the user.

Limitations

Research Use Only

Storage

Antibodies diluted in glycerol can be kept at 4ºC for up to 2 months and should be kept at -20ºC for long-term storage (1 year). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. After the maximum long-term storage period (1 year -20ºC or 2 months 4ºC) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy.

Product datasheet

Huntingtin-Interacting Protein 1 (HIP1) Rabbit Polyclonal Antibody

SKU: MM-0031
100 µL

Overview

Target

Huntingtin-Interacting Protein 1 (HIP1)

Target background

Hungtinton’s disease (HD) is an inherited neurodegenerative disorder characterized by the expression of an expanded polyglutamine tract in the protein huntingtin. HIP1 (huntingtin interacting protein 1) binds to normal huntingtin but this interaction is lost in HD. HIP1 also binds to components of clathrin-coated pits and vesicles and is a marker of clathrin-coated membranes. HIP1 expression levels are altered in several types of cancer.

Target alias

HIP1

Immunogen

peptide in C term

Specificity

The antibody recognizes the C-terminal portion of HIP1

Clone ID

---

Preservative

None

Format

Immunogen affinity purified in glycerol/PBS pH7.4

Recommend starting dilution

If diluted with deionized water in 100 µL: WB 1:500-1:2500; IF 1:10-1:100. Optimal dilution has to be determined by the user.

Limitations

Research Use Only

Storage

Antibodies diluted in glycerol can be kept at 4ºC for up to 2 months and should be kept at -20ºC for long-term storage (1 year). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. After the maximum long-term storage period (1 year -20ºC or 2 months 4ºC) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy.