Staufen, RNA binding protein homolog 2, is a member of the family of double-stranded RNA-binding proteins. Staufen 2 is mainly expressed in brain and heart tissues. Staufen 2 is found in the somatodendritic domain of neurons and colocalizes with microtubules in dendrites. The exact function of Staufen 2 is not yet known, but it could be involved in events involving double-stranded RNA-binding