MédiMabs Clones
A blog about science
Beyond Irreversibility: Restoring the Brain’s Recycling Fleet to Combat Alzheimer’s Disease
While prior studies report NAD+ depletion in Alzheimer’s disease (AD) models and partial attenuation of pathology with NAD+ precursor supplementation (1), the “more is better” approach has its limits. High doses of NAD+ precursors can produce supraphysiologic levels that may promote cancer, making them a risky long-term solution. In a recent study in Cell Reports […]
Latest articles
My name is σ…. PTPσ
The central nervous system (CNS) is a crucial anatomical compartment for brain functions where cellular mechanisms are tightly regulated. One...
MédiMabs’ Team • Jun 03 • 2 min
My chemical romance
As unromantic as it sounds, love results from biological responses to various neuropeptides and neurotransmitters (1). As such, love is...
MédiMabs’ Team • Feb 14 • 4 min
Tales from the lab – HIV-Flow
In this most terrifying time of year, We've chosen to open and peer,Into our well-guarded tomes of fear. Between the recipe for...
MédiMabs’ Team • Oct 17 • 5 min
The symphony and its conductor: The multiple and subtle effects of TC-PTP.
Immune response, inflammation, cell proliferation, and cell survival are all functions controlled by various signaling pathways. The combination of these...
MédiMabs’ Team • Oct 03 • 4 min
Tell me what you eat and I’ll tell you who you are.
Ingestion of DNA damaged by cooking as a new mechanism of carcinogenicity.As the saying goes "tell me what you eat...
MédiMabs’ Team • Aug 03 •
As with origami, you don’t always end up with a swan. SOD1 misfolded conformers and ALS.
Protein folding is like doing origami where the amino acid sequence dictates how the protein folds to form its final...
MédiMabs’ Team • Jun 15 • 3 min
Targeting the right suspect: DNA Vaccination strategies in Alzheimer’s Disease
Alzheimer's disease (AD) is one of the most common neurodegenerative disorders and the most common cause of dementia. It is...
MédiMabs’ Team • May 17 • 3
Identify inducible and replication-competent reservoirs: finding a needle in a haystack
Antiretroviral therapy (ART) blocks HIV viral cycle, but does not eliminate latently infected cells. A minority of proviruses integrated among...
MédiMabs’ Team • Apr 21 • 3
Radioactive payload attached to cancer-specific antibodies
In the past few decades, research efforts have focused on transitioning cancer treatments from a systemic approach to being able...
MédiMabs’ Team • May 26 • 3 min
Stop playing Whac-A-Mole with HIV: A promising new therapeutic strategy.
Due to the HIV's capacity to hide into different cell reservoirs, an effective therapy would be to reduce the viral...
MédiMabs’ Team • Jun 17 • 4
