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A blog about science
When Brain Beavers Build Too Big: Breaking the Glycogen Dam in Tauopathy
In the complex landscape of neurodegenerative disorders like Alzheimer’s disease and frontotemporal lobar degeneration (FTLD), an interesting case of metabolic misbehavior has been identified by a research team at the Buck Institute of Research on Aging (1). Think of glycogen, the brain’s emergency energy reserve, as the building material. In affected neurons, the tau protein […]
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MédiMabs’ Team • Feb 14 • 4 min
Tales from the lab – HIV-Flow
In this most terrifying time of year, We've chosen to open and peer,Into our well-guarded tomes of fear. Between the recipe for...
MédiMabs’ Team • Oct 17 • 5 min
The symphony and its conductor: The multiple and subtle effects of TC-PTP.
Immune response, inflammation, cell proliferation, and cell survival are all functions controlled by various signaling pathways. The combination of these...
MédiMabs’ Team • Oct 03 • 4 min
Tell me what you eat and I’ll tell you who you are.
Ingestion of DNA damaged by cooking as a new mechanism of carcinogenicity.As the saying goes "tell me what you eat...
MédiMabs’ Team • Aug 03 •
As with origami, you don’t always end up with a swan. SOD1 misfolded conformers and ALS.
Protein folding is like doing origami where the amino acid sequence dictates how the protein folds to form its final...
MédiMabs’ Team • Jun 15 • 3 min
Targeting the right suspect: DNA Vaccination strategies in Alzheimer’s Disease
Alzheimer's disease (AD) is one of the most common neurodegenerative disorders and the most common cause of dementia. It is...
MédiMabs’ Team • May 17 • 3
Identify inducible and replication-competent reservoirs: finding a needle in a haystack
Antiretroviral therapy (ART) blocks HIV viral cycle, but does not eliminate latently infected cells. A minority of proviruses integrated among...
MédiMabs’ Team • Apr 21 • 3
Radioactive payload attached to cancer-specific antibodies
In the past few decades, research efforts have focused on transitioning cancer treatments from a systemic approach to being able...
MédiMabs’ Team • May 26 • 3 min
Stop playing Whac-A-Mole with HIV: A promising new therapeutic strategy.
Due to the HIV's capacity to hide into different cell reservoirs, an effective therapy would be to reduce the viral...
MédiMabs’ Team • Jun 17 • 4
A potential target to stop Zika from replicating
Better than swatting mosquitoes...The Zika virus outbreak is a global health emergency since 2016. The virus mainly transmitted by mosquito...
MédiMabs’ Team • Feb 26 • 5 min
